To compare the chemo-sensitivity of NSCLC cell lines (A549, H460 and H2170) versus MSC variants (MSC-WT/wild-type, MSC-EV/empty-vector, MSC-TRAIL), cells were treated with serially diluted concentration of either cisplatin, 5-FU or vinorelbine for 48 h. The gene discussed is TNFSF10; the disease is non-small cell lung carcinoma.