HPGD and lung cancer: These analyses demonstrated that mRNA expression of G6PD, glutaminase (GLS), hydroxy-prostaglandin dehydrogenase 15-(NAD) [HPGD], TKT, TALDO1, ribulose-5-phosphate-3-epimerase (RPE), and transketolase-like-1 (TKTL1) were more abundant in lung cancer patient samples (Figure 5A).