In tumor tissues, four protective genes (JAK2, IL2RG, EEF1E1, and UBB) showed relatively low expression in the high‐risk group; in contrast, the expression of four risk genes (EPS8, FOXO1, STAT5A, and PAPPA) was more highly in the high‐risk group than that in the low‐risk group. This evidence concerns the gene PAPPA and neoplasm.