TP53 and cancer: We thus conclude that the energy supply and demand in irradiated cancer cells are orchestrated by mutations in several cancer-promoting genes, e.g., RAS and TP53, which are also linked, among others, to DNA repair capacity (Hähnel et al., 2014; Krause et al., 2016; Liu et al., 2015; Toulany et al., 2016) and survival (Viale et al., 2014).