Among 1,876 patients with non-metastatic breast cancer, 63.1% received chemotherapy (53.0%; anthracycline- and taxane-based regimens, 41.4%; anthracyclines only, 5.2%; taxanes alone), 63.1% received adjuvant radiotherapy, while approximately 20% of patients (126/618) with human epidermal growth factor receptor 2 (HER2) positive tumours received trastuzumab (not shown). The gene discussed is ERBB2; the disease is neoplasm.