As shown in the volcano plot (Supplementary Fig. 6b, c), SU decreased GZMB expression and upregulated genes related to inflammatory activation (FOS, JUN, NFKBIA, DUSP2, JAK1, PIM1), tumor immunity (CD47, PCBP2, EIF5A, PDIA3, EGR1), and DNA damage (H2AFX, DDIT3, GADD45B). Here, CD47 is linked to neoplasm.