We found that for HHcy patients, coronary artery disease was more severe that presented with multi-vessel disease (61.4% vs. 50.3%), more frequent non-culprit vessels chronic total occlusion (14.9% vs. 9.8%), and significant increases in Pro-BNP (628 (1311, 2125) vs. 265 (680, 1324) pg/mL) in the hypertension patients. Here, NPPB is linked to coronary artery disorder.