The serum levels of IL-6, IFN-γ, IL-10, and IL-17A were higher in HCMVpp65422-439-immunized mice at 12 weeks post-immunization (24 weeks of age, lupus group) compared with NZB/W F1 mice treated with PBS (control group) or adjuvant only (adjuvant group, Fig. 1b–e). This evidence concerns the gene IL6 and systemic lupus erythematosus.