To obtain further evidence that Pax5 induces the CD81 expression, we evaluated the correlation between CD81 and Pax5 in human tumor cell lines derived from different tissues: neuronal cell (SHSY5Y), epithelial cells (H1299, A549, MCF7, 293T, HeLa, SW480, and ME180), and B-lymphoma cells (BJAB, Ramos, Raji, Akata, MutuIII and BC3). Here, PAX5 is linked to neoplasm.