AIF1 and ischemic stroke: To determine whether the aforementioned infiltrating peripheral macrophages were expressing LILRB2, we immunolabeled tissues and found a dense distribution of LILRB2 +/Iba1+ macrophages in the ischemic zone at 7 DPI (Fig. 4e), compared to controls and other post-ischemic stroke time points (Supplementary Fig. 5b).