YBX3 and precursor B-cell acute lymphoblastic leukemia: We observed that pediatric B-ALLs with above-median YBX3 expression are associated with worse prognosis (Fig. 7d, hazard ratio = 2.03, P = 0.032, log-rank test), whereas adult B-ALL patients (that mainly comprise Ph+ B-ALLs) show no significant difference in survival (Fig. 7d).