Expression levels for genes such as NLRP3, NLRC4, TLR5, NOD, IL-1β, and IL-18 showed intricate interconnection that could eventually lead to a robust inflammasome gene profile, while in sepsis non-survivors, a higher magnitude of the same gene modulation pattern were observed, revealing its clinical relevance with sepsis severity.51 This evidence concerns the gene TLR5 and Sepsis.