POMC and congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency: In terms of adrenocortical function (chemiluminescence immunoassay), LCAH patients manifested as a low level of all adrenal hormones with a significant increase in ACTH; 11β-OHD patient was mainly characterized by elevated 17OHP and androgen; 3β-HSD deficiency patient was characterized by a significant increase in DHEAS; and patient with PORD suffered 17OHP increasing slightly with normal androgen levels.