Human KLF16 recombinant protein lessened MDA level, accelerated SOD, GSH and GSH-PX levels, and weakened IL-1β, IL-6, TNF-α and INF-γ levels in heart tissue of mice with myocardial ischemia-reperfusion (Figure 2(h-o)). Here, KLF16 is linked to myocardial ischemia.