Anti-KLF16 body also accelerated MDA level, lessened SOD, GSH and GSH-PX levels, and promoted IL-1β, IL-6, TNF-α and INF-γ levels in heart tissue of mice with myocardial ischemia-reperfusion (Figure 3(h-o)). The gene discussed is KLF16; the disease is myocardial ischemia.