In the pathological context of T2D in humans, ABCB10 variant rs348330 (G/A) has been consistently associated with a higher risk to develop T2D (p-value 3.37e-21, OR of 0.957), with this significant association to T2D being preserved after adjusting for obesity (BMI) (p-value 2.709e-8, OR of 0.9484) [1,17,18]. Here, ABCB10 is linked to obesity due to melanocortin 4 receptor deficiency.