The presence of some proteins (i.e., histone-lysine N-methyltransferase (MLL3), α-microglobulin/bikunin precursor (AMBP), and voltage-dependent anion-selective channel protein 1 (VDAC1)) in uEVs were observed in samples from diabetic nephropathy patients [113]. Here, VDAC1 is linked to diabetic kidney disease.