PSAP and infection: During the development of Bt infection in the midgut of CPB larvae, induction of some detoxification system components have been determined, such as esterases, GST, cytochrome p450 monooxygenase, glutathione synthetase and saposins (prosaposin-like precursors) and cathepsin-proteases that take part in the lysosomal destruction of endogenic and exogenic molecules [23].