AKT1 and breast carcinoma: Among them, several signaling pathways have been described to be deregulated in breast carcinoma, including the PI3K/Akt/mTOR pathway, Notch pathway, Hedgehog pathway, ERK/MAPK pathway, NF-kB pathway, FOXO1/JAK/STAT pathway, TP53 pathway, Wnt/β-catenin, as well as apoptotic and cell cycle pathways.