PON1 and atherosclerosis: Lyso-diacylglyceryltrimethylhomoserine MGTS (20:5) has been identified as the compound responsible for increasing the activity of Paraoxonase 1 (PON1) in macrophages, an enzyme known to exert beneficial effects in several processes related to atherosclerosis thanks to its strong anti-inflammatory and antioxidant activities [54].