Several risk factors lead to the incidence of diabetes and complications, including BMI (body mass index), extra visceral fat, diabetes onset at an early age, significant historical changes over the last decade, cardiovascular disease (CVD), insufficient β-cell response to counter insulin resistance, high alcohol intake, sedentary lifestyle, obesity or being overweight, high rate of childhood obesity, gestational diabetes, and increased inflammatory markers [13]. Here, INS is linked to diabetes mellitus.