Several type 2 diabetes mellitus (T2DM) susceptibility loci have been identified in or near GLIS3, PEPD, FITM2-R3HDML-HNF4A, KCNK16, MAEA, GCC1-PAX4, PSMD6, and ZFAND [11]. The gene discussed is HNF4A; the disease is type 2 diabetes mellitus.