In addition, the transaminase serum concentrations (aspartate aminotransferase (ASAT), +36%, p = 0.027; alanine aminotransferase (ALAT), +27%, p = 0.005) as well as the homeostasis model assessment of insulin resistance (HOMA-IR, +69%, p = 0.006) were significantly increased in the obese patients. The gene discussed is ABCB7; the disease is Insulin resistance.