By comparison, traditional multivariable logistic regression analysis showed that younger recipient age; kidney retransplantation; ECD deceased donor utilization; dialysis duration; PRA; recipient HIV seropositivity; degree of HLA mismatch; DGF; basiliximab induction; and cyclosporine, azathioprine, and mTOR inhibitor-based immunosuppression were independent risk factors for acute rejection among Black kidney transplant recipients. Here, MTOR is linked to kidney transplant.