IL4 and type 2 diabetes mellitus: Interestingly though, a significant positive correlation between F-GLP-1 and the relative IL-4/IFN-γ expression (representing a Th2 shift [17]) was detected in the T2D group (r = 0.4057, p < 0.05, Figure 3e), and remained after controlling for HbA1c (r = 0.501, p < 0.05).