Although hypoalbuminemia has been repeatedly reported as a predictor of mortality in COVID-19 (Violi et al., 2020; Huang et al., 2020), low albumin levels may result from surgery, dialysis, abdominal infections, liver failure, pancreatitis, respiratory distress, bypass surgery, ovarian problems caused by fertility drugs, and many other conditions. The gene discussed is ALB; the disease is liver failure.