In contrast, our data of TE4 cells (a miR205HG‐low expressed ESCC cell lines) with miR205HG overexpression revealed that the ectopic miR205HG enhances MYH11 and SPINK5 expression but suppressed BGN, COL10A1, COL5A1, MMP1, MMP3, and IL1B expression (Fig. 2F,G). The gene discussed is MMP3; the disease is esophageal squamous cell carcinoma.