However, judged from their onset ages in childhood (which are not so popular in MS or AQP4-Ab-positive NMOSD), good recovery in neurological disturbances after the first attack, types of the first clinical episode, and distributions of the CNS lesions of the first attack, it can be inferred that their first clinical episodes in their childhood could be related to the presence of MOG-Ab, and might be able to be included in the series of attacks related to MOGAD. This evidence concerns the gene AQP4 and myeloid sarcoma.