CCDC80 and cancer: Moreover, the results of KEGG enrichment identified that CCDC80-related downregulated DEGs were enriched in the “Ras signaling pathway,” “Axon guidance,” and “Proteoglycans in cancer,” etc., while CCDC80-related upregulated DEGs may be involved in “DNA replication” and “Base excision repair,” etc. (Figure 7, Table S1).