HOTAIR and cancer: While well-known lncRNAs, such as H19, Metastasis associated lung adenocarcinoma transcript 1 (MALAT1), or HOX antisense intergenic RNA (HOTAIR), are reported as pan-cancer markers across different tissues, newly discovered lncRNAs [e.g., long intergenic non-coding RNA 01111 (LINC01111) in PDAC] have also been shown to work as biomarkers for several cancers (Pandya et al., 2020; Takahashi, Yan et al., 2014a).