LINC-ROR and cancer: Linc-RoR works as an oncogene in several cancers (Pan et al., 2016), enhances the cellular tolerance to hypoxic stress by acting as a miRNA sponge to miR-145, and promotes chemoresistance to anti-cancer drugs by inducing stem cell-like properties, as shown in HCC (Takahashi et al., 2014b; Takahashi et al., 2014c).