We found that the transcripts DAAM1 and PAICS, which are translated into proteins predicted as potentially interacting with SARS-CoV-2, were also highly co-expressed with DPP4 and CTSL. These results demonstrate that, although ACE2 and TMPRSS2 are poorly expressed in the placenta, other mediators that potentially interact with the virus are highly co-expressed in villous trophoblast cells and, therefore, may represent a valuable alternative route for infection and viral replication. Here, CTSL is linked to infection.