HAVCR2 and acute myeloid leukemia: In both malignancies, TIGIT+ and TIM-3+ cells were significantly more frequent among the Vδ1 subpopulation in comparison to the Vδ2 subpopulation (AML: p = 0.006, p = 0.014 and MM: p = 0.001, p = 0.042; Figures 4A,B).