IFNG and neoplasm: In oncology, both the Vδ1 and Vδ2 T cells have been described to exert pleiotropic effector functions: as mentioned above the tumor-infiltrating IFNγ-producing γδ T cell fraction has shown cytotoxic effects in solid and hematological malignancies (7, 12, 13), whereas interleukin (IL)-17- and galectin 1-secreting γδ T cells promote tumor growth and the recruitment of immunosuppressive myeloid cells (14, 15).