For AML, our analyses revealed an increased expression of TIGIT and TIM-3 on γδ T cells and CD8+ T cells in comparison to CD4+ T cells (γδ T cells vs. CD4: for TIGIT p = 0.01, for TIM-3 p < 0.001, and CD8 vs. CD4: for TIGIT p = 0.006, for TIM-3 p = 0.01; Figure 3A). The gene discussed is CD8A; the disease is acute myeloid leukemia.