LncRNA KTN1-AS1 was upregulated in several tumors, such as non-small cell lung cancer, bladder cancer, head and neck squamous cell carcinoma, and hepatocellular carcinoma and promoted the progression of tumors (Zhang et al., 2019; Jiang et al., 2020; Hu et al., 2021; Li Y. Y. et al., 2021). Here, KTN1 is linked to head and neck squamous cell carcinoma.