GSDME and hepatocellular carcinoma: The high expression of CASP1, CASP3, CASP5, CASP6, CASP8, GPX4, GSDMA, GSDME, NLRC4, NLRP3, NLRP7, NOD1, NOD2, PLCG1, and SCAF11 correlated with the poor survival of the HCC patients, as indicated by the Hazard ratio (HR) > 1 (Figure 2A).