Studies later identified linked hereditary PCa regions for the following candidate familial PCa susceptibility genes: hereditary prostate cancer gene 1 (HPC1) as RNASEL (Ribonuclease L), HPC2 (Hereditary Prostate Cancer gene 2) as ELAC2 (ElaC Ribonuclease Z 2) and 8p22-23 as MSR1 (Macrophage Scavenger Receptor 1) (87). This evidence concerns the gene RNASEL and prostate cancer.