BRCA2 and aggressive behavior: With OR’s (Odds ratio) ranging from 4 to 15 in the combined study sample of AA and Ugandan men, rare pathogenic variants within ATM (ATM Serine/Threonine Kinase gene), BRCA2, PALB2 (Partner and Localizer of BRCA2) and NBN (Nibrin) genes were observed to be associated with increased risk of aggressive disease (113).