IL20RA mRNA expression was found to be upregulated in CRC compared with the level in normal tissue in the Oncomine (IL20RA in Skrzypczak colorectal dataset, fold change = 2.034, P value = 1.63E −16) and GEO databases (IL20RA in GSE10950 colorectal dataset, fold change = 1.996, FDR = 1.88E −14), which was consistent with our results on IL20RA protein expression in CRC. Here, IL20RA is linked to colorectal carcinoma.