Among them, MAPK8 (Slattery, Lundgreen & Wolff, 2012), HSPB1 (Nadin et al., 2012), IL1B (Sanabria-Salas et al., 2017), PRIM1 (Cloutier et al., 1997) and so on were shown to be associated with the susceptibility to or prognosis of CRC. Here, PRIM1 is linked to colorectal carcinoma.