When p value < 0.05, 11 TFs with regulatory effects on the core prognostic genes were obtained (Table 4), including a number of cancer-related transcription factors, such as activating transcription activator 1 (ATF1), CCAAT/enhancer binding proteins C/EBP beta (CEBPB), E2F transcription Factor 3 (E2F3), ETS translocation variant 4 (ETV4), and Y-box protein 1 (YBX1). The gene discussed is CEBPB; the disease is cancer.