Among them, MAPK8 (Slattery, Lundgreen & Wolff, 2012), HSPB1 (Nadin et al., 2012), IL1B (Sanabria-Salas et al., 2017), PRIM1 (Cloutier et al., 1997) and so on were shown to be associated with the susceptibility to or prognosis of CRC. This evidence concerns the gene IL1B and colorectal carcinoma.