ADAM17 and idiopathic pulmonary fibrosis: MiR-708-3p is downregulated in plasma and tissues from IPF patients, and overexpression of miR-708-3p attenuates lung fibrogenesis through directly modulating its target a disintegrin and metalloproteinase 17 (ADAM17), which regulates immune responses, fibrosis, and tissue regeneration, and by GATA/STAT3 signal pathway that is implicated in fibroblast-myofibroblast differentiation (Liu et al., 2018b).