TAB3 and idiopathic pulmonary fibrosis: The downregulation of miR-30a-5p is shown in exosomes from bronchoalveolar lavage fluid (BALF) of IPF elderly patients and A549 cells, its overexpression downregulates α-smooth muscle actin, and fibronectin expression by targeting TGF-β activated kinase 1/MAP3K7 binding protein 3 (TAB3), which is implicated in various cellular processes such as immune and inflammatory responses, altered fibrosis, and tissue repair and remodeling involved in IPF pathogenesis (Liu et al., 2018a).