The downregulation of miR-30a-5p is shown in exosomes from bronchoalveolar lavage fluid (BALF) of IPF elderly patients and A549 cells, its overexpression downregulates α-smooth muscle actin, and fibronectin expression by targeting TGF-β activated kinase 1/MAP3K7 binding protein 3 (TAB3), which is implicated in various cellular processes such as immune and inflammatory responses, altered fibrosis, and tissue repair and remodeling involved in IPF pathogenesis (Liu et al., 2018a). Here, FN1 is linked to idiopathic pulmonary fibrosis.