FOXD3 and acute myeloid leukemia: In a related study, overexpression of LINC00449 could inhibit acute myeloid leukemia cell invasion and cell proliferation in vitro and in vivo, and the LINC00449/miR-150/FOXD3 signaling pathway may be a novel prognostic biomarker or therapeutic target for the treatment of acute myeloid leukemia (Shi et al., 2020b).