CDKN2A and aneurysmal bone cyst: In contrast, mutations in genes encoding proteins implicated in B-cell receptor signaling and the nuclear factor kappa-light-chain-enhancer of activated B cells pathway (such as CD79b and MYD88) and genes involved in the regulation of the cell cycle (such as CDKN2A) contribute to the molecular pathogenesis of ABC DLBCL5,19,20.