When comparing the germinal center B-cell (GCB) DLBCLs (n = 17) with the activated B-cell (ABC) DLBCLs (n = 9), PIM1 mutations were present only in the patients with GCB DLBCL (41% vs. 0%; p = 0.03), and XPO1 mutations were present only in the patients with ABC DLBCL (22% vs. 0%; p = 0.08), with statistically significant differences (Supplementary Fig. 1). Here, PIM1 is linked to diffuse large B-cell lymphoma.