While analyzed ADAMTS13 activity within tertile groups by multivariate Cox proportional hazards model, patients in the low tertile group (ADAMTS13 activity, range 7–29%) have a hazard ratio of 14.56 (95% CI 1.81–116.91, p = 0.01) to develop new cardiovascular events after adjusting comorbid DM and CHD (Table 3). This evidence concerns the gene ADAMTS13 and diabetes mellitus.