Interestingly, when a foreign antigen Ovalbumin (OVA) was introduced into B16/F10 cells, this tumor growth acceleration was diminished (Supplementary Fig. 2c), suggesting that tumor immunogenicity could be one of the factors that dictate the anti-tumor or pro-tumor effect of T cell-intrinsic LSD1 depletion. This evidence concerns the gene KDM1A and neoplasm.