In addition, although the total number of CD8+ T cells in tumor-draining lymph nodes (TdLNs) was reduced by LSD1 depletion (Supplementary Fig. 3a–d), OVA-specific CD8+ T cells in TdLNs were numerically comparable between the two groups of mice carrying MC38-OVA tumors (Supplementary Fig. 3e, f), suggesting CD8+ T cell priming in response to the tumor growth is mostly unaffected by LSD1 depletion. Here, CD8A is linked to neoplasm.