A panel of nine NB cell lines (CLB-BAR, CLB-GAR, CLB-GE, IMR-32, Kelly, NB-1, SHSY5Y, SK-N-AS, SK-N-BE(2)), which represent a range of aberrant genetic backgrounds found in NB tumours (Supplementary Table 1), were examined for the presence of ATR/pATR and the related PIKK ATM/pATM, and its downstream signalling components FOXM1/pFOXM1 as well as CHK1/pCHK1. The gene discussed is ATR; the disease is neuroblastoma.