The observation of ATR/ATM PIKK phosphorylation motifs suggested a potential role for ATM or ATR and examination of publicly available phosphoproteomic data regarding SUN2 (including the www.phosphosite.org database) suggested that SUN2 phosphorylation has been frequently identified in anti-ATM/ATR substrate motif antibody-based experiments in cancer cells. Here, SUN2 is linked to cancer.