TGFB1 and breast cancer: These observations are comparable to previous reports by our laboratory on the contribution of TGFβ, YAP/TAZ, and canonical Wnt signaling to EMT in breast cancer cells, where TGFβ has been found to be epistatic to YAP/TAZ, and where Wnt/β-catenin signaling also exerts a critical yet rather auxiliary function to both cell proliferation and EMT (Diepenbruck et al, 2014; Meyer-Schaller et al, 2019; Buechel et al, 2021).