A previous study for PAH patients, PASMCs, and hypoxia-induced PAH rats showed that miR-145 could promote hypoxia-induced proliferation and migration of PASMCs by regulating ATP-binding cassette expression subfamily A member 1(ABCA1), which suggested that miR-145 might involve in the pathogenesis of PAH [32]. Here, ABCA1 is linked to pulmonary arterial hypertension.