GPRC5A and pancreatic adenocarcinoma: Interestingly, besides the strong correlation between GPRC5A and IMUP genes expression indicating their potentially similar biological functions and close involving signaling pathways in PAAD, the aberrant higher expression of both genes were indicated to be relating with worse patients both overall survival and recurrence free survival, supported not only by previous online analysis, but also IHC experiments using local hospital PAAD tissue array which was produced using 62 local PAAD patients samples and matched normal pancreatic tissues.