CDH2 and hepatocellular carcinoma: We, likewise, discovered that miR-140-3p upregulation resulted in suppressive effects on the viability, proliferation, migration and invasion of LUAD cells, and took initiative to validate the downregulation of miR-140-3p caused the decrease of E-cadherin yet the increase of both N-cadherin and vimentin in LUAD cells, which was similar to the results of a prior discovery that the upregulated miR-140-3p was associated with the reduced N-cadherin and vimentin expressions yet promoted E-cadherin expression in hepatocellular carcinoma (HCC) cells [28].