Prior studies have suggested that the increased caspase-3 activity in LUAD cells A549 and Calu3 is associated with the upregulation of miR-140-3p, while the decreased Bcl-2 is associated with the elevation of Bax and cleaved caspase-3 in cervical cancer cell Caski [13,35]. The gene discussed is CASP3; the disease is cervical cancer.