CD4+ and CD8+ T cells, NK cells, conventional type 1 dendritic cells (cDC1s) and cDC2s, NK cells, and neutrophils were all recruited to the tumor over the course of 6 days following a single dose of AIPV, and the CD8/Treg ratio shifted dramatically (Figures S1B and S1C). The gene discussed is CD8A; the disease is neoplasm.