One day post treatment with AI, IP, AP, or ICB, the number of apoptotic tumor cells was doubled compared with untreated tumors, but tumor cell death was increased 3-fold following treatment with AIP, and these cells exposed calreticulin that promotes phagocytosis (Chao et al., 2010) (Figures 2B and 2C). This evidence concerns the gene CALR and autoimmune pancreatitis.