The data revealed widely decreased levels of host metabolic enzymes such as argininosuccinate synthase (ASS1), glutamine synthetase (GLUL), phosphoglycerate mutase 1 (PGAM1), glyoxylate and hydroxypyruvate reductase (GRHPR), NADH: ubiquinone oxidoreductase subunit B6 (NDUFB6), NFS1 cysteine desulfurase (NFS1), pyruvate dehydrogenase E1 component subunit alpha (PDHA1), SDHB, and serine hydroxymethyltransferase 2 (SHMT2) after infection. The gene discussed is PGAM1; the disease is infection.