Although pathogenic variants in MYH7 are associated with hypertrophic cardiomyopathy, dilated cardiomyopathy, and left ventricular noncompaction and pathogenic variants in SDHA have been associated with Leigh syndrome (severe movement disorder), pheochromocytoma, and paragangliomas, the cardiovascular examination did not reveal any structural abnormalities, and there were no documented features consistent with Leigh syndrome, pheochromocytoma, or parangangliomas at autopsy. This evidence concerns the gene MYH7 and Leigh syndrome.