The inhibition of OM on endosomal TLRs was validated by measuring the downstream cytokine production, where the levels of IL‐6 and MCP‐1 secreted by THP‐1 cell‐derived macrophages were significantly reduced by OM under PolyI/C (Figure 4e) or R848 (Figure 4f) stimulation. Here, IL6 is linked to ocular melanoma.