TNF and psoriasis: In Australia, the biologics available for psoriasis are the tumor necrosis factor-alpha (TNF-α) inhibitors: adalimumab, infliximab, and etanercept; the interleukin (IL)-12/23 inhibitor: ustekinumab; the IL-17 inhibitors: secukinumab and ixekizumab; and the IL-23 inhibitors: guselkumab, risankizumab, and tildrakizumab.2